Cagrilintide Dosage Calculator

What Is Cagrilintide?

Cagrilintide is an experimental long-acting acylated synthetic amylin receptor agonist (non-selective agonist of AMYR1, AMYR2, and AMYR3 receptors). Engineered with a C18 fatty acid side chain, Cagrilintide binds to human serum albumin, extending its biological elimination half-life to approximately 159 hours (nearly 7 days).

In preclinical and clinical research, Cagrilintide mimics endogenous pancreatic amylin, delaying gastric emptying, suppressing glucagon secretion, and signaling satiety through central area postrema networks. It is frequently studied in combination with GLP-1 receptor agonists such as Semaglutide or dual agonists like Tirzepatide. Reconstituting Cagrilintide with our peptide calculator and bacteriostatic water guarantees exact dosage conversion.

Cagrilintide Dosage Chart

Cagrilintide research titration schedules start at 0.3 mg (300 mcg) weekly and escalate up to 2.4 mg. Reconstituting a 5 mg vial with 2.0 mL of bacteriostatic water creates a concentration of 2.5 mg/mL (12 units = 0.3 mg).

Vial: 2 mgWater: 2.0 mL

Concentration1.0 mg/mL

Target Dose0.3 mg (300 mcg)

Draw to Mark:30.0 Units

Vial: 5 mgWater: 2.0 mL

Concentration2.5 mg/mL

Target Dose0.3 mg (300 mcg)

Draw to Mark:12.0 Units

Vial: 5 mgWater: 2.0 mL

Concentration2.5 mg/mL

Target Dose0.6 mg (600 mcg)

Draw to Mark:24.0 Units

Vial: 10 mgWater: 2.0 mL

Concentration5.0 mg/mL

Target Dose1.2 mg (1,200 mcg)

Draw to Mark:24.0 Units

Vial Size	Bac Water Added	Concentration	Target Research Dose	Draw Units (U-100)
2 mg	2.0 mL	1.0 mg/mL	0.3 mg (300 mcg)	30.0 Units
5 mg	2.0 mL	2.5 mg/mL	0.3 mg (300 mcg)	12.0 Units
5 mg	2.0 mL	2.5 mg/mL	0.6 mg (600 mcg)	24.0 Units
10 mg	2.0 mL	5.0 mg/mL	1.2 mg (1,200 mcg)	24.0 Units

How to Reconstitute Cagrilintide

Reconstituting acylated Cagrilintide requires gentle fluid introduction to prevent fatty-acid side chain aggregation.

Syringe Reading Diagram

U-100 Syringe Graduation & Measurement Line (Cagrilintide)

5 Standard Reconstitution Steps for Cagrilintide

Sanitize rubber stoppers of both vials with 70% isopropyl alcohol prep pads.
Draw 2.0 mL of sterile bacteriostatic water into a syringe.
Inject water slowly down the interior glass wall of the Cagrilintide vial.
Swirl gently until the powder fully dissolves into a clear liquid solution.
Refrigerate reconstituted solution at 2°C–8°C.

❄️ Storage & Shelf-Life Notice (Cagrilintide)

Reconstituted Cagrilintide prepared with Bacteriostatic Water is stable for up to 28 days under refrigeration (2°C–8°C). Protect from heat and light.

⚠️ Common Preparation Mistakes to Avoid

Shaking violently, using unpreserved sterile water, and freezing liquid reconstituted solutions.

Cagrilintide Dosing FAQ

How much bac water do I add to 5mg Cagrilintide?↓

Adding 2.0 mL of bac water to a 5 mg Cagrilintide vial yields a concentration of 2.5 mg/mL. A 0.3 mg (300 mcg) dose equals 12 units on a U-100 syringe.

What is Cagrilintide?↓

Cagrilintide is a long-acting acylated amylin analogue researched for satiety induction and synergistic metabolic research alongside GLP-1 agonists.

What is the half-life of Cagrilintide?↓

Cagrilintide has an elimination half-life of approximately 159 hours (about 7 days).

How many units is 0.6 mg Cagrilintide on a 5mg vial with 2mL water?↓

With 2.0 mL of water in a 5 mg vial (2.5 mg/mL), a 0.6 mg dose equals 24 units (0.24 mL).

Can Cagrilintide be combined with Semaglutide in studies?↓

Yes. Dual research protocols investigate Cagrilintide and Semaglutide co-administration for dual amylin and GLP-1 receptor activation.